Alliance iS PDA System

Alliance iS PDA HPLC System

Alliance iS Quaternary Solvent Manager (QSM)
The Quaternary Solvent Manager (QSM) is a low-pressure mixing pump that can blend up to four degassed solvents (A, B, C, and D). A gradient proportioning valve (GPV) is used to dynamically blend solvents in any specified combination, producing repeatable and reproducible gradient segments regardless of solvent compressibility and system back pressure. Integrated degasser chambers (one per solvent line) automatically remove dissolved gases from up to four elution solvents.
The QSM features:
•Automated, continuous compressibility compensation for accurate and precise delivery at pressures up to 12,000 psi (~827 bar)
•Programmable flow rates that range from 0.001 to 10.000 mL/min
•Leak sensors to manage and identify solvent leaks during unattended operation

Alliance iS Sample Manager (SM)
The Alliance iS Sample Manager manages the temperature of a sample, aspirates precise volume of sample, and injects sample into the mobile phase using a flow-through- needle (FTN) design. The needle becomes part of the fluidics path when the sample is injected onto the column. The mobile phase cleanses the needle during the run, ensuring complete sample recovery and minimizing carryover. Additionally, the sample positioning mechanism controls the location of the sample plates relative to the sample needle, reducing extra system volume. The standard configuration supports sample injection volumes of 0.1 to 100 μL. The sample temperature is regulated within a range of 4 °C (39.2 °F) to 40 °C (104 °F).
The SM features:
•Three-plate sample capacity
•Precise sample metering
•Accurate sample temperature control
•Exceptional carryover performance (0.002% maximum)
•Consistent solvent consumption
•Puncture robustness
•Leak sensors to manage and identify solvent leaks during unattended operation

Alliance iS Column Heater Cooler (CHC) 30CM with RFID
The Column Heater Cooler (CHC) is a compartment in the system that controls the thermal environment of a single column using a combination column heater and cooler. When the compartment temperature is set, either directly from the console or within a method, a command is sent to the CHC that switches the compartment heating/cooling engine on or off. The CHC continues to heat or cool until the compartment achieves the specified temperature set point.
The CHC features:
•Integrated passive preheating
•Temperature setting range between 4 °C (39.2 °F) to 90 °C (194 °F)
•Column clips for easy column removal and replacement
•Tool-free fittings
•Leak sensors to manage and identify solvent leaks during unattended operation

Supported configurations include:
•Column length: 300 mm (maximum)
•Column ID: 8 mm (maximum)
•Column guard or column in-line filter: 50 mm (maximum)

Alliance iS PDA Detector (PDA)
The PDA Detector offers advanced optical detection, providing unprecedented trace impurity detection and quantitation in conjunction with spectral analysis capabilities along with a TaperSlit™ stainless steel flow cell, allowing this detector to exhibit very low noise. It is the ideal detector for any lab application from compound identification to method development. For routine analyses, the PDA detector is reliable, easy-to-use, and has enhanced software control to provide flexibility for simultaneous 2D and 3D operation.